The 59-year-old actor announced his injury and postponed Hollywood Vampires' US tour on social media.
Johnny, who performs with Alice Cooper and Joe Perry, stated on Instagram: "My dear friends, I am sorry to report that I have broken my ankle, which is a drag!!!
Between Cannes and the Royal Albert Hall, the hairline break worsened. I can't go since many doctors advised me to avoid all exercise.
"To that end, the lads and I am extremely sorry to miss you in New Hampshire, Boston, and New York but worry not, I guarantee we will offer a great concert to all of you in Europe.
"Johnny's doctor recommended him not to travel after his previous performances due to a severe ankle ailment.
"He feels devastated by this turn of events, but looks toward resting up so all four Vampire can bring their best performance to the tour in Europe."
LIKE AND SHARE